El banco de medición de caudal Raman es un componente clave del sistema de ensamblaje de flujo Raman que lleva la espectroscopia Raman al bioprocesamiento posterior. Este sistema de ensamblaje de flujo Raman satisface las demandas de velocidad de la etapa posterior al optimizar la recolección Raman para muestras de bajo volumen y baja turbidez. Ideal para caudales a escala de desarrollo, proporciona monitoreo de procesos en tiempo real, optimización rápida y control para cromatografía y otras operaciones unitarias posteriores.
Procesos de separación y purificación: agregación, cristalización de proteínas, estabilidad de la fórmula, atributos críticos de calidad (CQA) del producto, concentración de proteínas, excipientes de solución amortiguadora
Transporte y almacenamiento: monitorización de analitos en el permeado
Ventajas
El banco de caudal Raman contiene una célula de caudal Raman y se conecta fácilmente a una sonda Rxn-10 combinada con un analizador integrado Raman Rxn
Proporciona información del proceso basada en la tecnología Raman y un control de las operaciones unitarias del bioprocesamiento de procesos de separación y purificación
Incorpora un control de luz ambiental, así como una amplificación de la señal
Tecnología de espectroscopia Raman, tecnología avanzada de análisis óptico
Mejore la seguridad de su planta, garantice la calidad de su producto y optimice sus operaciones. La espectroscopia Raman mide la composición y estructura molecular en tiempo real a partir de muestras tomadas en proceso con calidad de laboratorio.
Medición de procesos de separación y purificación de biosimilares con la tecnología Raman: prueba del proceso de purificación de proteínas durante la ultrafiltración/diafiltración (UF/DF) de Alvotech
Prioritize scalability for an efficient biopharmaceutical
product development lifecycle
PU (publicación)
Versión en checo - 09/2024
New version available in English
This technical paper studies the importance of scalability as a competitive advantage in bioprocessing in the Life Science industry, and Endress+Hauser's scalable Raman systems (Raman Rxn2, Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve, flow cell and flow bench, Raman optic system for single use) and liquid analysis sensor technology and Liquid Analysis portfolio (Liquiline CM44P, CM442 and OUSAF44, OUSBT66 and Memosens CPS61E, CLS82E, COS81E, CLS82E).
Endress+Hauser - your one-source Life Sciences technology partner
PU (publicación)
Versión en inglés - 06/2024
New version available in English
Graphic highlighting why Endress+Hauser is trusted by the world's top biopharmaceutical manufacturers for its Life Sciences expertise and reliable inline, real-time measurement technologies like Raman spectroscopy systems (Raman Rxn2, Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve, flow cell and flow bench, Raman optic system for single use) and liquid analysis sensor technology (Liquiline CM44P, CM442 and OUSAF44, OUSBT66 and Memosens CPS61E, CLS82E, COS81E, CLS82E).
Prioritize scalability for an efficient biopharmaceutical
product development lifecycle
PU (publicación)
Versión en inglés - 06/2024
New version available in English
This technical paper studies the importance of scalability as a competitive advantage in bioprocessing in the Life Science industry, and Endress+Hauser's scalable Raman systems (Raman Rxn2, Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve, flow cell and flow bench, Raman optic system for single use) and liquid analysis sensor technology and Liquid Analysis portfolio (Liquiline CM44P, CM442 and OUSAF44, OUSBT66 and Memosens CPS61E, CLS82E, COS81E, CLS82E).
Raman calibration and verification kits - Everything needed to
calibrate and verify your Raman analyzer system for lab-to-process
scalability
PU (publicación)
Versión en inglés - 12/2023
New version available in English
An overview of the Raman calibration and verification kits for the bio multi optic / single use optic and the Raman flow assembly (includes the flow bench and flow cell). These kits are to be used in conjunction with the Rxn-10 probe and Raman Rxn2 / Rxn4 analyzer for upstream and downstream bioprocessing (powered by Kaiser Raman technology).
Raman flow assembly - Precise composition measurement of
high-speed, low-volume samples in downstream bioprocessing
PU (publicación)
Versión en inglés - 05/2023
New version available in English
An overview of the Raman flow assembly (flow bench and flow cell) used with the Rxn-10 probe in conjunction with a Raman Rxn2 analyzer and a Raman flow assembly calibration and verification kit for downstream bioprocessing (powered by Kaiser Raman technology).
Endress+Hauser - your one-source Life Sciences technology partner
PU (publicación)
Versión en checo - 09/2024
New version available in English
Graphic highlighting why Endress+Hauser is trusted by the world's top biopharmaceutical manufacturers for its Life Sciences expertise and reliable inline, real-time measurement technologies like Raman spectroscopy systems (Raman Rxn2, Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve, flow cell and flow bench, Raman optic system for single use) and liquid analysis sensor technology (Liquiline CM44P, CM442 and OUSAF44, OUSBT66 and Memosens CPS61E, CLS82E, COS81E, CLS82E).
Lab-to-process monitoring & control in Life Sciences -
Reliable measurement of bioprocess physical and
chemical properties
PU (publicación)
Versión en inglés - 04/2024
New version available in English
A combined product list of analysis offerings from both Optical Analysis and LIquid Analysis for bioprocessing applications in the life science industry (including Raman Rxn2 analyzer, Raman Rxn4 analyzer, Rxn-10 probe, bio multi optic and bio sleeve, Raman flow assembly, Rxn-45 probe, Rxn-46 probe, Raman optic system for single use, Memosens CPS61E, Memosens COS81E, OUSBT66, Memosens CPS61E, Memosens CPS77E, Memosens CLS82E, OUSAF44, Memosens CPS11E, Memosens CLS16E, TOC Analyzer CA79, Liquiline transmitter platform, and Memobase software).
Faster market entry, higher yields, and improved
quality - Real-time, inline bioprocess monitoring and
control from lab to GMP with Raman Rxn systems &
Memosens digital sensors
Catálogo de competencia (CP)
Versión en inglés - 06/2024
New version available in English
This eBook highlights the Endress+Hauser inline analysis portfolio for bioprocessing including Raman spectroscopy systems (Raman Rxn2, Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve, flow cell and flow bench, Raman optic system for single use) and liquid analysis sensor technology (Liquiline CM44P, CM442 and OUSAF44, OUSBT66 and Memosens CPS61E, CLS82E, COS81E, CLS82E) in the Life Science industry.
Faster market entry, higher yields, and improved
quality - Real-time, inline bioprocess monitoring and
control from lab to GMP with Raman Rxn systems &
Memosens digital sensors
Catálogo de competencia (CP)
Versión en checo - 09/2024
New version available in English
This eBook highlights the Endress+Hauser inline analysis portfolio for bioprocessing including Raman spectroscopy systems (Raman Rxn2, Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve, flow cell and flow bench, Raman optic system for single use) and liquid analysis sensor technology (Liquiline CM44P, CM442 and OUSAF44, OUSBT66 and Memosens CPS61E, CLS82E, COS81E, CLS82E) in the Life Science industry.
Raman downstream process measurement of biosimilars -
Alvotech's monitoring of the protein purification process
during ultrafiltration / diafiltration (UF/DF)
Estudio de caso (CS)
Versión en inglés - 06/2024
New version available in English
This case study examines Alvotech's use of Raman systems (Raman Rxn2 analyzer with Rxn-10 probe and Raman flow assembly) to monitor the downstream protein purification process during UF/DF.
Cell line development meets Raman spectroscopy -
KBI Biopharma’s monitoring of a diverse array of cell
lines and cell concentrations in minimal volume for
automated cell cultivation
Estudio de caso (CS)
Versión en inglés - 12/2024
New version available in English
A case study demonstrating how KBI Biopharma uses Endress+Hauser's Raman spectroscopy system (Raman Rxn2 analyzer, Rxn-10 probe, and the Raman flow assembly's flow bench and flow cell) to screen for cell growth performance during cell line development.
Raman downstream process measurement of biosimilars -
Alvotech's monitoring of the protein purification process
during ultrafiltration / diafiltration (UF/DF)
Estudio de caso (CS)
Versión en checo - 09/2024
New version available in English
This case study examines Alvotech's use of Raman systems (Raman Rxn2 analyzer with Rxn-10 probe and Raman flow assembly) to monitor the downstream protein purification process during UF/DF.
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